Gas phase preparation of magnetic nanoparticle hydrosols
Başlık çevirisi mevcut değil.
- Tez No: 401692
- Danışmanlar: PROF. CHRIS BINNS
- Tez Türü: Doktora
- Konular: Fizik ve Fizik Mühendisliği, Physics and Physics Engineering
- Anahtar Kelimeler: Belirtilmemiş.
- Yıl: 2014
- Dil: İngilizce
- Üniversite: University of Leicester
- Enstitü: Yurtdışı Enstitü
- Ana Bilim Dalı: Fizik Ana Bilim Dalı
- Bilim Dalı: Belirtilmemiş.
- Sayfa Sayısı: 138
Özet
Özet yok.
Özet (Çeviri)
The main purpose of this work was to produce nanoparticles with a pure iron core, a narrow size distribution and a high saturation magnetisation in order to improve their effectiveness in the hyperthermia treatment of tumours and in Magnetic Resonance Imaging (MRI) diagnosis. Gas phase Fe nanoparticles in a liquid suspension have been produced by co-deposition with water vapour in ultra-high vacuum (UHV) conditions. The water was injected from outside the vacuum as a molecular beam onto a substrate maintained at 77 K and formed an ice layer with a UHV compatible vapour pressure. Various coating ligands were added to the injected water in an attempt to stabilise the nanoparticle hydrosols. Transmission Electron Microscopy (TEM) images confirmed that the nanoparticles had a pure iron core with a thin oxide shell and a narrow size distribution with the most probable diameter of either 8.55 or 16 nm depending on the source conditions. It was found that short chain molecules are more effective in stabilising the gas phase nanoparticles. The size distribution of the nanoparticles in liquid suspensions analysed by a Nanosight LM10 particle sizer showed that, of the ligands tested, sorbitol and DMSA are the most suitable to prevent the agglomeration of the gas phase produced hydrophobic nanoparticles. UV-visible spectral measurements showed that DMSA coated nanoparticles transform into an oxide in a short time. In addition, a magnetometry study of sorbitol-coated iron nanoparticles showed that oxidation of the nanoparticles erodes the pure iron core to about 5 nm diameter in two months. MRI measurements of the sorbitol-coated iron nanoparticles show that their relaxivity is five times higher than commercial iron oxide nanoparticle suspensions (Resovist®). On the other hand, specific absorption rate (SAR) measurements of the nanoparticles by two different designs of heating coils were not accurate due to the low concentration of nanoparticle in solution. Hence, the heating performance of the nanoparticles was determined theoretically using a new model published by Vallejo-Fernandez [Vallejo-Fernandez 2013], which includes the heating mechanisms active over the whole size range of particles. The results show that the SAR of the pure iron core nanoparticles is significantly higher than iron oxide nanoparticles. Core-shell nanoparticle can also be produced in the gas phase by passing the core nanoparticles through hot crucible loaded with the shell material under UHV conditions. Composite Fe@FeO-Ag nanoparticles which can be used for multifunctional medical applications have been produced. It was also found that heating the nanoparticles in the gas phase using the empty crucible enabled the control of the nanoparticles' shapes, which was found to change their MRI relaxivity.
Benzer Tezler
- Cu ve CuNi nanopartiküllerinin çözelti yanma senteziyle üretimi ve karakterizasyonu
Production and characterisation of Cu and CuNi nanoparticles with solution combustion synthesis
MUSTAFA ÇAĞRI ALTINBAŞ
Yüksek Lisans
Türkçe
2022
Metalurji Mühendisliğiİstanbul Teknik ÜniversitesiMetalurji ve Malzeme Mühendisliği Ana Bilim Dalı
DOÇ. DR. MEHMET ŞEREF SÖNMEZ
- Ultrasonik sprey piroliz (USP) yöntemi ile nano yapılı kurşun oksit üretimi ve karakterizasyonu
Production and characterization of nano structured lead oxide via ultrasonic spray pyrolysis (USP)
BURAK AŞIK
Yüksek Lisans
Türkçe
2012
Metalurji Mühendisliğiİstanbul Teknik ÜniversitesiMetalurji ve Malzeme Mühendisliği Ana Bilim Dalı
PROF. DR. SEBAHATTİN GÜRMEN
- Iron based magnetic nanoparticles: Synthesis using different production methods, encapsulation with silica/graphene, characterization and performance tests
Demir esaslı manyetik nanopartiküller: Farklı metotlar kullanarak sentezlenmesi, silika/grafen ile enkapsülasyonu, karakterizasyonu ve performans testleri
SIDDIKA MERTDİNÇ ÜLKÜSEVEN
Doktora
İngilizce
2023
Metalurji Mühendisliğiİstanbul Teknik ÜniversitesiMetalurji ve Malzeme Mühendisliği Ana Bilim Dalı
PROF. DR. MUSTAFA LUTFİ ÖVEÇOĞLU
DOÇ. DR. DUYGU AĞAOĞULLARI
- Fiziksel buhar biriktirme (Pvd) yöntemiyle yapılan Alüminyum krom nitrür (AlCrN) ince film kaplamaların üretimi ve karakterizasyonu
Production and characterization of Aluminium chromium nitride (AlCrN) thin films deposited by Physical vapour deposition (Pvd)
TUNCAY AKBAL
Yüksek Lisans
Türkçe
2014
Metalurji Mühendisliğiİstanbul Teknik ÜniversitesiMetalurji ve Malzeme Mühendisliği Ana Bilim Dalı
PROF. DR. MUSTAFA KAMİL ÜRGEN
- Mo-N esaslı PVD kaplamaların oksidasyon davranışları
The oxidation behaviour of Mo-N coatings deposited on alumina by cathodic ARC PVD method
MURAT KESİK
Yüksek Lisans
Türkçe
1997
Metalurji Mühendisliğiİstanbul Teknik ÜniversitesiMetalurji Mühendisliği Ana Bilim Dalı
DOÇ. DR. M. KELAMİ ŞEŞEN