Köpeklerde deneysel olarak oluşturulan septik şokun sağaltımında Dobutamine, Flunixin, Meglumine, Methylprednisolone ve Enalapril'in etkileri
Başlık çevirisi mevcut değil.
- Tez No: 58874
- Danışmanlar: DOÇ. DR. HASAN BATMAZ
- Tez Türü: Doktora
- Konular: Veteriner Hekimliği, Veterinary Medicine
- Anahtar Kelimeler: Belirtilmemiş.
- Yıl: 1997
- Dil: Türkçe
- Üniversite: Uludağ Üniversitesi
- Enstitü: Sağlık Bilimleri Enstitüsü
- Ana Bilim Dalı: İç Hastalıkları (Veterinerlik) Ana Bilim Dalı
- Bilim Dalı: Belirtilmemiş.
- Sayfa Sayısı: 83
Özet
SUMMARY In experimentally septic shock induced dogs, establishment of early diagnostic criteria and comparison of the affects of different treatment combinations at the beginning of the septic shock were aimed in this study. Thirty dogs of both sexes and different ages were used in the study. To clinically and hematologically controlled each dogs, 5x1 09 Escherichia coli bacteria/kg were given via intravenous route and approximately within one hour the septic shock was induced. Five groups each composed of 6 dogs were designed, and to I th group (control group) only antibiotic and fluid therapy was performed. To rest of the groups, along with antibiotic and fluid therapy, at the beginning dobutamin (10 meg/kg/min, i.v.) was given. Additionally, methylprednisolone sodium succinate (in the shock phase 30 mg/kg, i.v.), flunixin meglumin (in the shock phase and 2 nd and 12 th hours of the shock 1.5 mg/kg, i.v.), and enalapril (after 24 th hour 0.5 mg/kg, Per oral in every 12 hours), were utilized to the III. rd, IV. th and V. th groups, respectively. All the dogs were examined regarding for clinical, hematological and biochemical parameters before and at the septic shock phase and also at the 1 st, 4 th. 12 th, 24 th, 36 th, 48 th, 72 nd, 96 th and 120 th hours after the application of first treatment. Plasma volume was calculated from hematocrit and hemoglobin values. During the septic shock high fever, increased heart and respiratory rates, weakned heart beat and peripheral pulse, prolonged capillary refilling time, leukopenia, neutropenia, thrombocytopenia, plasma volume decrease and increased hematocrit (p
Özet (Çeviri)
SUMMARY In experimentally septic shock induced dogs, establishment of early diagnostic criteria and comparison of the affects of different treatment combinations at the beginning of the septic shock were aimed in this study. Thirty dogs of both sexes and different ages were used in the study. To clinically and hematologically controlled each dogs, 5x1 09 Escherichia coli bacteria/kg were given via intravenous route and approximately within one hour the septic shock was induced. Five groups each composed of 6 dogs were designed, and to I th group (control group) only antibiotic and fluid therapy was performed. To rest of the groups, along with antibiotic and fluid therapy, at the beginning dobutamin (10 meg/kg/min, i.v.) was given. Additionally, methylprednisolone sodium succinate (in the shock phase 30 mg/kg, i.v.), flunixin meglumin (in the shock phase and 2 nd and 12 th hours of the shock 1.5 mg/kg, i.v.), and enalapril (after 24 th hour 0.5 mg/kg, Per oral in every 12 hours), were utilized to the III. rd, IV. th and V. th groups, respectively. All the dogs were examined regarding for clinical, hematological and biochemical parameters before and at the septic shock phase and also at the 1 st, 4 th. 12 th, 24 th, 36 th, 48 th, 72 nd, 96 th and 120 th hours after the application of first treatment. Plasma volume was calculated from hematocrit and hemoglobin values. During the septic shock high fever, increased heart and respiratory rates, weakned heart beat and peripheral pulse, prolonged capillary refilling time, leukopenia, neutropenia, thrombocytopenia, plasma volume decrease and increased hematocrit (p
Benzer Tezler
- Dopaminin septik şokta böbrek hemodinamiği ve morfolojisi üzerindeki etkilerinin köpeklerde deneysel olarak incelenmesi
Başlık çevirisi yok
LÜTFİ TELCİ
- Deneysel septik şokta glukagonun böbrek hemodinamiği ve morfolojisine etkileri
Başlık çevirisi yok
YILMAZ BAŞAR
- Deneysel sepsisde doku oksijenasyonunun değerlendirilmesinde gastrik tonometri ile pentoksifillin kullanımının doku oksijenizasyonuna etkisi
Başlık çevirisi yok
CANDAN DEMİRKOL
Tıpta Uzmanlık
Türkçe
2000
Anestezi ve ReanimasyonGATAAnesteziyoloji ve Reanimasyon Ana Bilim Dalı
PROF.DR. MERİH GÖKBEN
- Köpeklerde deneysel olarak oluşturulan karaciğer toksikasyonunun tanısında adenozin deaminazın önemi
The Significence of adenosine deaminase in experimental toxicosis of liver in dogs
NURİ ALTUĞ
Yüksek Lisans
Türkçe
1999
Veteriner HekimliğiYüzüncü Yıl Üniversitesiİç Hastalıkları (Veterinerlik) Ana Bilim Dalı
PROF.DR. ZAHİD TEVFİK AĞAOĞLU
- Köpeklerde deneysel olarak oluşturulan karaciğer toksikasyonlarında klinik , hematolojik, biyokimyasal ve ultrasonografik bulgular
Clinical, hematologic, biochemical and ultrasonographic findings in experimentally induced liver toxications in dogs
MEHMET TÜTÜNCÜ
Doktora
Türkçe
1998
Veteriner HekimliğiYüzüncü Yıl Üniversitesiİç Hastalıkları (Veterinerlik) Ana Bilim Dalı