Bazı (2-benzimidazolil) propanoik asit türevleri üzerinde çalışmalar
Başlık çevirisi mevcut değil.
- Tez No: 31605
- Danışmanlar: PROF. DR. NİNGUR NOYANALPAN
- Tez Türü: Yüksek Lisans
- Konular: Eczacılık ve Farmakoloji, Pharmacy and Pharmacology
- Anahtar Kelimeler: Benzimidazoller, Farmakoloji, Kromatografi-ince tabaka, Manyetik rezonans spektroskopi, Propionatlar, Benzimidazoles, Pharmacology, Chromatography-thin layer, Magnetic resonance spectroscopy, Propionates
- Yıl: 1993
- Dil: Türkçe
- Üniversite: Gazi Üniversitesi
- Enstitü: Sağlık Bilimleri Enstitüsü
- Ana Bilim Dalı: Farmasötik Kimya Ana Bilim Dalı
- Bilim Dalı: Belirtilmemiş.
- Sayfa Sayısı: Belirtilmemiş.
Özet
- 67 ) - (CH2)2CONH-R Table - 4 Compound I, II, III, XI, XII and XIII were reperted by other outhors in the literature beforea<*. Synthesis of the title compounds have been succeeded in four steps starting from o-phenylendiamine. Chemical structure of the compounds have been elucidated by the data of their IR and NMR spectra and elemental analyses. The elemental analyses of the compounds reported in the literature have not been performed.- 68 Antifungal activity of the 13 title compounds have been investigated against four yeast-like fungi (Candida albicans. Candida pseudotropicalis. Candida parapsilosis. Cryptococcus neoformans). All the ^compound have showed promising antifungal activity against the fungi employed. However especially compound XII and XIII which are thiosemicarbazide derivatives have been found more potent than the others in general.- 67 ) - (CH2)2CONH-R Table - 4 Compound I, II, III, XI, XII and XIII were reperted by other outhors in the literature beforea<*. Synthesis of the title compounds have been succeeded in four steps starting from o-phenylendiamine. Chemical structure of the compounds have been elucidated by the data of their IR and NMR spectra and elemental analyses. The elemental analyses of the compounds reported in the literature have not been performed.
Özet (Çeviri)
- 68 Antifungal activity of the 13 title compounds have been investigated against four yeast-like fungi (Candida albicans. Candida pseudotropicalis. Candida parapsilosis. Cryptococcus neoformans). All the ^compound have showed promising antifungal activity against the fungi employed. However especially compound XII and XIII which are thiosemicarbazide derivatives have been found more potent than the others in general.- 67 ) - (CH2)2CONH-R Table - 4 Compound I, II, III, XI, XII and XIII were reperted by other outhors in the literature beforea<*. Synthesis of the title compounds have been succeeded in four steps starting from o-phenylendiamine. Chemical structure of the compounds have been elucidated by the data of their IR and NMR spectra and elemental analyses. The elemental analyses of the compounds reported in the literature have not been performed.- 68 Antifungal activity of the 13 title compounds have been investigated against four yeast-like fungi (Candida albicans. Candida pseudotropicalis. Candida parapsilosis. Cryptococcus neoformans). All the ^compound have showed promising antifungal activity against the fungi employed. However especially compound XII and XIII which are thiosemicarbazide derivatives have been found more potent than the others in general.
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