Geri Dön

Vision Guided Automation for Intracytoplasmic Sperm Injection

Başlık çevirisi mevcut değil.

  1. Tez No: 716892
  2. Yazar: FERHAT SADAK
  3. Danışmanlar: Belirtilmemiş.
  4. Tez Türü: Doktora
  5. Konular: Biyokimya, Biyomühendislik, Biochemistry, Bioengineering
  6. Anahtar Kelimeler: Belirtilmemiş.
  7. Yıl: 2020
  8. Dil: İngilizce
  9. Üniversite: The University of Birmingham
  10. Enstitü: Yurtdışı Enstitü
  11. Ana Bilim Dalı: Belirtilmemiş.
  12. Bilim Dalı: Belirtilmemiş.
  13. Sayfa Sayısı: 127

Özet

Özet yok.

Özet (Çeviri)

Biological cell injection is an effective technique in which a foreign material is directly introduced into the target cell. Intracytoplasmic Sperm Injection (ICSI) is a microinjection technique which is used for infertility treatment. In this technique, a single sperm cell is directly injected into an oocyte using micropipettes. The operations in this application are manually controlled by an embryologist and more importantly, this reduces the accuracy, repeatability, and consistency of the operation. Therefore, the full automation is a prerequisite for microinjection operations, particularly in ICSI application. This thesis focuses on enhancing the microinjection procedure by developing vision-guided processes prior to and during the operation. Initially, a vision-controlled technique was proposed to align the injection and holding pipettes in three orthogonal axes which is essential for successful microinjection. To conduct reliable injection, the vibrational displacement of the injection pipette's tip needs to be evaluated and improved before the operations continue further. A novel vision-based sensor was developed to measure the displacement changes at the tip in three orthogonal axes. By employing the developed vision sensor, the effect of injection speed on vibrational displacement creation was analysed to determine the value of various injection parameters, such as force fluctuation, and penetration force on cell damages. An ultimate automation task is required in microinjection to position the randomly located biological cell within the Petri dish to the system's field of view. The proposed technique fills a gap in the literature by proposing a real-time cell recognising and positioning system that can be employed with different types of biological cells at various maturation stages, as well as with different microscope types that are being used in microinjection applications.

Benzer Tezler

  1. Bilgisayar yardımıyla makina konstrüksiyonu ve asansör tahrik grubuna ait CAD programı

    Computer aided machine construction and CAD program for elevator driving group

    CEVAT ERDEM İMRAK

    Yüksek Lisans

    Türkçe

    Türkçe

    1992

    Makine Mühendisliğiİstanbul Teknik Üniversitesi

    PROF. DR. HAMİT ÖZTEPE

  2. Yapay Zeka'nın robot görmesi üzerine uygulanması

    An Application of robot vision in artificial intelligence

    FUNDA PEHLİVAN

    Yüksek Lisans

    Türkçe

    Türkçe

    1992

    Makine Mühendisliğiİstanbul Teknik Üniversitesi

    PROF. DR. TALHA DİNİBÜTÜN

  3. Esnek üretim sistemlerinin tasarımı ve çizelgelemesi

    Design and scheduling of flexible manufacturing systems

    AHMET MURAT PORAY

    Yüksek Lisans

    Türkçe

    Türkçe

    1995

    Endüstri ve Endüstri Mühendisliğiİstanbul Teknik Üniversitesi

    DOÇ.DR. M. BÜLENT DURMUŞOĞLU

  4. Değişim mühendisliği

    Başlık çevirisi yok

    ESRA SEZGİN

    Yüksek Lisans

    Türkçe

    Türkçe

    1996

    Endüstri ve Endüstri Mühendisliğiİstanbul Teknik Üniversitesi

    DOÇ.DR. MEHMET TANYAŞ