Zayıflama diyetlerinde kullanılan balık yağının hemostatik aktivite ve biyokimyasal parametrelere etkisine yönelik bir araştırma
A research; the efeect of fish oil that is used in losing weight diet on haemostatic activity and biochemical parameters
- Tez No: 156898
- Danışmanlar: PROF.DR. H. TANJU BESLER
- Tez Türü: Doktora
- Konular: Beslenme ve Diyetetik, Nutrition and Dietetics
- Anahtar Kelimeler: Obesity, haemostatic factors, fibrinolytic system, Q-3 fatty acids, cardiovascular disease, low calori diet, leptin
- Yıl: 2004
- Dil: Türkçe
- Üniversite: Hacettepe Üniversitesi
- Enstitü: Sağlık Bilimleri Enstitüsü
- Ana Bilim Dalı: Beslenme ve Diyetetik Ana Bilim Dalı
- Bilim Dalı: Belirtilmemiş.
- Sayfa Sayısı: Belirtilmemiş.
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Özet (Çeviri)
VI ABSTRACT Nişancı, F., A research; the effect of fish oil that is used in losing weight diet on haemostatic activity and biochemical parameters. Hacettepe University, Institute of Health Sciences PhD Thesis in Nutrition and Dietetics, Ankara, 2004. Female patients who were admitted to Diet Clinic Of Turkey Yüksek ihtisas Hospital with the purpose of losing weight, were included to our study. They were 30-45 years old and their body mass index values were between 30-35 kg/m". Twenty cases in study group took 1000 mg fish oil added to the losing weight diet, on the other hand 20 cases in control group took only the losing weight diet. The cases in the study group and in the control group lost 9.9 % and 10.2% of body weight respectively. Antrophometric measurements of both groups were significantly decreased (p< 0.05). Systolic and diastolic blood pressures were reduced 12.6% and 14.6% respectively in the study group, and 10.2% and 10.7% respectively in the control group (p<0.05). Total cholesterol were reduced 7.5% (p< 0.05) in the study group,6.1% (p>0.05) in the control group. The difference in HDL and LDL cholesterol of the study group were not statistically significant (p>0.05). Increase in HDL - C and decrease in LDL - C of the control group were statistically significant (p<0.05). Triglyseride were reduced 14.6% in the study population (p>0.05) and 28% in the control group (p<0.05). Plasma fibrinogen levels were increased 3.1% in the study group (p>0.05) and 13.8% in the control group (p<0.05). There were no statistically significant difference in alfa 2 anti plasmin and plasminogen values of both groups. Plasma PAI-1 levels were increased statistically significant in the study group (p<0.05), whereas the increase in the control group was not statistically significant. Protein C were increased statistically significant in both groups (p<0.05). Increase in the Protein S values were not statistically significant in the study group, but statistically significant in the control group (p<0.05). Antithrombin HI, Factor V, Factor VIII and Factor X were increased statistically significant in both groups (p<0.05). Plasma leptin levels decreased 28.9 % in the study group and 16.3 % in the control group. It was statistically significant in both groups. Similarly plasma CRP levels decreased statistically significant in study and control groups (p<0.05). (16.7 % vs 8.3 %, respectively). Food intake of patients in study and control groups were examined and it was found that in the study group it was 55.8 % carbohydrate, 18.9 % protein, 25.2 % fat and in the control group it was 55.6 % carbohydrate, 19.2 5 % protein, 25.1 % fat. When it was compared with RDA % values, it was found that energy, carbohydrate, fat and cholesterol levels were lower than the recommended ranges (100 %) whereas protein and some vitamin levels were higher than the recommended ranges.
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