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İnvazif mesane tümörü nedeni ile radikal sistoprostatektomi sonrası üriner diversiyon uygulanan hastalarda postoperatif dönemde meydana gelen metabolik, fizyolojik ve histopatolojik değişiklikler

Postoperative metabolic, physiologic and histopathologic changes in the patients which undergone urinary diversion following radical cystoprostatectomy

  1. Tez No: 33082
  2. Yazar: TEMUÇİN ŞENKUL
  3. Danışmanlar: PROF. DR. YAVUZ ÖNOL
  4. Tez Türü: Tıpta Uzmanlık
  5. Konular: Üroloji, Urology
  6. Anahtar Kelimeler: Belirtilmemiş.
  7. Yıl: 1995
  8. Dil: Türkçe
  9. Üniversite: GATA
  10. Enstitü: Haydarpaşa Eğitim Hastanesi
  11. Ana Bilim Dalı: Üroloji Ana Bilim Dalı
  12. Bilim Dalı: Belirtilmemiş.
  13. Sayfa Sayısı: 83

Özet

SUMMARY Postoperative metabolic, physiologic and histopathologic changes in the patients which undergone urinary diversion following radical cystoprostatectomy due to invasive bladder cancer. Between 1986 to 1995, 49 male patients with invasive bladder tumor were treated by urinary diversions following radical pelvic surgery. Of the 49 urinary diversions, 29 were ileal conduit, 16 were orthotopic neobladder and 4 were ureterosigmoidostomy. The patients with ureterosigmoidostomy were excluded because 3 patients did not come to routine follow-ups and 1 patient was undiverted to orthotopic neobladder. Technical properties of the operations, peroperative and early postoperative complications were recorded. The postoperative evaluations included serum electrolytes and blood gas analyzes, histopathologic changes in the mucosa of ileal conduit and neobladder, potency and continence status, urodynamic studies, function of upper urinary tract and tumor progression. Early complication rates were 12,4% and 13,8% in the patients with orthotopic neobladder and ileal conduit, respectively. Late complication rates were 6,2% and 6,8% in the patients with orthotopic neobladder and ileal conduit, respectively. Although, serum chloride levels increased in 13 patients (86%) with orthotopic neobladder, their blood gas analyzes were normal. All patients with ileal conduit had increased serum chloride levels but hyperchloremic metabolic acidosis developed in only 1 patient. The increase of the serum chloride levels was statistically significant in both groups (p

Özet (Çeviri)

SUMMARY Postoperative metabolic, physiologic and histopathologic changes in the patients which undergone urinary diversion following radical cystoprostatectomy due to invasive bladder cancer. Between 1986 to 1995, 49 male patients with invasive bladder tumor were treated by urinary diversions following radical pelvic surgery. Of the 49 urinary diversions, 29 were ileal conduit, 16 were orthotopic neobladder and 4 were ureterosigmoidostomy. The patients with ureterosigmoidostomy were excluded because 3 patients did not come to routine follow-ups and 1 patient was undiverted to orthotopic neobladder. Technical properties of the operations, peroperative and early postoperative complications were recorded. The postoperative evaluations included serum electrolytes and blood gas analyzes, histopathologic changes in the mucosa of ileal conduit and neobladder, potency and continence status, urodynamic studies, function of upper urinary tract and tumor progression. Early complication rates were 12,4% and 13,8% in the patients with orthotopic neobladder and ileal conduit, respectively. Late complication rates were 6,2% and 6,8% in the patients with orthotopic neobladder and ileal conduit, respectively. Although, serum chloride levels increased in 13 patients (86%) with orthotopic neobladder, their blood gas analyzes were normal. All patients with ileal conduit had increased serum chloride levels but hyperchloremic metabolic acidosis developed in only 1 patient. The increase of the serum chloride levels was statistically significant in both groups (p

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