Non-invasive monitoring of gastric motility in humans
Mide hareketliliğinin insanlarda müdahalesiz ölçümü-elektrogastrografi
- Tez No: 198801
- Danışmanlar: YRD. DOÇ. DR. ATA AKIN
- Tez Türü: Yüksek Lisans
- Konular: Biyomühendislik, Biyoteknoloji, Gastroenteroloji, Bioengineering, Biotechnology, Gastroenterology
- Anahtar Kelimeler: Elektrogastrografi (EGG), diken dalga potansiyeli, gastrik motilite, gastrik\DYDúGDOJDOar, Electrogastrography (EGG), spike potential, gastric motility, gastric slow waves
- Yıl: 2005
- Dil: İngilizce
- Üniversite: Boğaziçi Üniversitesi
- Enstitü: Biyo-Medikal Mühendislik Enstitüsü
- Ana Bilim Dalı: Belirtilmemiş.
- Bilim Dalı: Belirtilmemiş.
- Sayfa Sayısı: 57
Özet
ÖZET0ø'(+$5(.(7/ø/øöø1ø1ø16$1/$5'$0h'$+$/(6ø=g/dh0h-(/(.752*$6752*5$)øMide, sindirim VLVWHPLQLQ |QHPOL RUJDQODUÃQGDQ ELULVLGLU YH PLGHQLQ WHPHO J|UHYL \HPHNERUXVX \ROX\OD NHQGLVLQH DNWDUÃODQ \L\HFHNOHUL \DSÃVÃQGD EXOXQDQ GÂ] NDV KÂFUHOHULQLQ ULWPikNDVÃOPDODUà YH VDOJÃODGÃֈ DVLW LoHULNOL VÃYÃ\à YH VLQGLULP HQ]LPOHULQL NXOODQDUDN VLQGLULPH X\JXQKDOHJHWLUPHNWLU0LGHPRWLOLWHVLQLQNRQWUROÂVDOJÃODQDQKRUPRQODUYHPLGHGÂ]NDVODUÃQÃQQ|UDONRQWURO \ROX\OD VD÷ODQPDNWDGÃU (OHNWURJDVWURJUDIL (**, mide düz kas hücrelerininVHUJLOHGL÷LPLGHPRWLOLWHVLQH \RODoDQHOHNWULNVHODNWLYLWH\LJHUHNVHUR]DOHOHNWURWODUNXOODQDUDNLQYD]LYJHUHNVHNDUÃQGXYDUÃQD\HUOHúWLULOHQ\Â]H\VHOHOHNWURWODUNXOODQÃODUDNQRQ-invaziv olarakölçülmesi yöntemidir. ElektURNDUGL\RJUDIL (.* YH (OHFWURHQVHIDORJUDIL ((* JLEL GL÷HU\Â]H\VHO HOHNWURIL]\RORMLN |OoÂP WHNQLNOHUL\OH NDUúÃODúWÃUÃOGÃ÷ÃQGD (** oRN \DYDú JHOLúLPJ|VWHUPLúWLU %XQXQ QHGHQOHUL PLGHGHQ JHOHQ HOHNWULNVHO VLQ\DOOHULQ ROGXNoD ]D\ÃI ROPDVà YHGÂúÂNVinyalJÂUÂOWÂRUDQÃQHGHQL\OHYHULWRSODPDQÃQJÂoROPDVÃ(**LOHNXOODQÃODELOLUYHULHOGH HWPHQLQ YH HOGH HGLOHQ YHULOHULQ NOLQLNOH RODQ LOLúNLOHULQLQ \RUXPODQPDVÃQÃQ ROGXNoD JÂoROPDVà (** YHULOHUL LOH JDVWULN PRWLOLWH DUDVÃQGDNL LOLúNLQLQ WDP RODUDN DQODúÃOÃS RUWD\DNRQXODPDPÃú ROPDVÃGÃU *DVWULN NDVÃOPDODUÃQ IUHNDQVà ³\DYDú GDOJDODU´ RODUDN QLWHOHQGLULOHQ YHIUHNDQVà JHQHOGH +] RODQ HOHNWULNVHO VLQ\DOOHU WDUDIÃQGDQ NRQWURO HGLOPHNWHGLU *DVWULNNDVÃOPDODUÃQúHNOLLVHGLNHQGDOJDDNWLYLWHVLLOHLOJLOLGLU*ÂQÂPÂ]GHNRQYDQVL\RQHO(**WHNQL÷LLOHGDKDoRNGÂúÂNIUHNDQVOÃVLQ\DOOHULQWRSODQPDVÃKHGHIOHQPHNWHGLUDQFDN\DSÃODQED]ÃKD\YDQoDOÃúPDODUÃQGDSHULVWDOWLNNDVÃOPDODUVÃUDVÃQGD\ÂNVHNIUHNDQVOÃVLQ\DOOHULQGHJ|UÂOHELOGL÷LWHVSLWHGLOPLúWLU %L]LP GH EX oDOÃúPDGDNL WHPHO DPDFÃPÃ] (** NXOODQDUDN LQVDQODUGD \ÂNVHNIUHNDQVOÃSHULVWDOWLNNDVÃOPDVLQ\DOOHULQLWRSODPDNYH\RUXPODPDNWÃU
Özet (Çeviri)
ABSTRACTNON-INVASIVE MONITORING OF GASTRIC MOTILITY IN HUMANSStomach is an organ of gastrointestinal system where the food coming from the mouththrough the esophagus is mixed by the rhythmic contractions of the smooth muscles, with acidand other gastric secretions. The control of motility of the stomach is performed by neuronal andhormonal factors that modulate the smooth muscles in generating muscular contractions.Electrogastrography is a procedure for recording gastric myoelectrical activity either invasivelyby placing electrodes on serosal lining of the stomach or non-invasively by using electrodeslocated on the skin of the abdomen. Compared with the development of other surfaceelectrophysiological measurements, such as Electrocardiogram (ECG) and Electroencephalogram(EEG), the progress of the EGG has been very slow. The main problems include: (1) difficulty indata acquisition and analysis because of the low signal-to-noise ratio of the EGG; (2) difficulty ininterpreting EGG data and extracting useful and relevant information from the EGG; and (3) lackof understanding of the correlation between the EGG and gastric motility. Today, numerousclinical and animal studies are being carried out by using EGG in order to have reliable, scientificdata which can help the interpretation of the findings. The frequency of gastric contractions iscontrolled by the gastric slow wave, which is around 3 cycles per minute (cpm) and theappearance of gastric contractions is associated with spike activities. Today, conventional EGGdevices are collecting data related with the lower frequency signals but it was shown on theanimal models that higher frequency signals observed during peristaltic contractions can also bedetected and quantified from EGG recordings by using a suitable method and perhaps, thepatterns of this high frequency components can be correlated with the pathological processesrelated with the stomach. Our main interest arises on the collection and interpretation of the highfrequency peristaltic contractions signals in humans using EGG.
Benzer Tezler
- Opere edilmiş erken evre mide kanseri hastalarında kemoterapi tedavisinin nüks üzerindeki etkisinin değerlendirilmesinde Sialidaz, Sialiltransferaz dengesi ve VEGF ile Endoglin düzeylerinin rolü
The role of Sialidase, Sialyltransferase balance and VEGF and Endoglin levels in the evaluation of the effect of chemotherapy treatment on recurrence in operated early stage gastric cancer patients.
NESLİHAN SUNGUR
Doktora
Türkçe
2025
BiyokimyaErciyes ÜniversitesiTıbbi Biyokimya Ana Bilim Dalı
PROF. DR. SABAHATTİN MUHTAROĞLU
PROF. DR. MEVLÜDE İNANÇ
- Pron pozisyonda PEEP uygulanmasının gastrik antrum çapına etkisi ve ekstübasyon öncesi aspirasyon riskinin değerlendirilmesi
The effect of PEEP application in prone position on gastric antrum diameter and evaluation of aspiration risk before extubation
SÜLEYMAN TAYGURT
Tıpta Uzmanlık
Türkçe
2024
Anestezi ve ReanimasyonSağlık Bilimleri ÜniversitesiAnesteziyoloji ve Reanimasyon Ana Bilim Dalı
UZMAN NİHAL GÖKBULUT ÖZASLAN
DR. SÜLEYMAN TAYGURT
- Experimental and mathematical investigation of mass transfer in food and hydrogel systems using magnetic resonance imaging and nMR relaxometry
Gıda ve hidrojel sistemlerinde kütle transferi sürecinin manyetik rezonans görüntüleme ve nMR relaksometre ile deneysel ve matematiksel incelenmesi
SEVİL ÇIKRIKCI
Doktora
İngilizce
2019
Gıda MühendisliğiOrta Doğu Teknik ÜniversitesiGıda Mühendisliği Ana Bilim Dalı
DOÇ. DR. HALİL MECİT ÖZTOP
PROF. DR. BEHİÇ MERT
- Tipik ve atipik gastro-özefageal reflü kliniği düşünülen çocuklarda reflü sıklığı ve tanıda pH monitorizasyonunun yeri
The prevalence of gastroesophageal reflux in children who had typical and atypical gastroesophageal reflux symptoms and sings and the place of pH monitorization in diagnosis
DEMET ALAGÖZ
Tıpta Uzmanlık
Türkçe
2009
Çocuk Sağlığı ve HastalıklarıDüzce ÜniversitesiÇocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
PROF. DR. BÜNYAMİN DİKİCİ
- Farklı primerler ve DNA izolasyon yöntemleri kullanarak polimeraz zincir reaksiyonu yöntemiyle dışkı örneklerinde helicobacter pylori varlığının araştırılması ve sonuçların immünokromatografik yöntemle karşılaştırılması
Investigation of presence of helicobacter pylori in fecal samples, by various primers and DNA isolation methods using polymerase chain reaction method and comparison of results with immunochromatographic detection method
SEVİL DİLEK KÖKÜM
Yüksek Lisans
Türkçe
2010
MikrobiyolojiKaradeniz Teknik ÜniversitesiTıbbi Mikrobiyoloji Ana Bilim Dalı
YRD. DOÇ. CELAL KURTULUŞ BURUK