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Multiple frequency bioelectrical impedance analysis to assess body fluid composition changes with altitude

İrtifada vücut kompozisyon değişikliklerini gözlemlemek için çok frekanslı biyoelektrik empedans analizi

  1. Tez No: 364506
  2. Yazar: FIRAT YEŞİLLETEN
  3. Danışmanlar: PROF. DR. YEKTA ÜLGEN
  4. Tez Türü: Yüksek Lisans
  5. Konular: Biyomühendislik, Bioengineering
  6. Anahtar Kelimeler: Belirtilmemiş.
  7. Yıl: 1995
  8. Dil: İngilizce
  9. Üniversite: Boğaziçi Üniversitesi
  10. Enstitü: Biyomedikal Mühendislik Enstitüsü
  11. Ana Bilim Dalı: Biyomedikal Mühendisliği Ana Bilim Dalı
  12. Bilim Dalı: Belirtilmemiş.
  13. Sayfa Sayısı: Belirtilmemiş.

Özet

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Özet (Çeviri)

In this study, the body fluid composition changes due to exposure to high altitude is assessed by multifrequency and multisite bioimpedance analysis. For this purpose a portable Bioimpedance Analyzer that is capable of measuring the resistance and the reactance of the tissues and body parts at five different frequencies is designed. To assess the effects of altitude, the instrument is used in performing multifrequency bioimpedance analysis on 10 subjects who participated in the third week of Kac;kar 94 Expedition. Kac;kar 94 Expedition ofBogaziC;i University Skin and Scuba Club (BUS AS) lasted for three weeks on Mt. Kac;kar (3412m.). The data are collected before, during and after the expedition and discussed to investigate the effects of altitude on body fluid composition changes. Based on the empirical formulas of previous studies, the Fat Free Mass is observed to decrease with high altitude due to the dehydration during the trip, the heavy activities causing depletion of fat reserves and by the effect of hypoxia which is a part of the acute mountain sickness. To question the overestimation in previous studies that use 50kHz bioimpedance analysis to assess body fluid changes with altitude, a different approach based on Cole-Cole plot that was used to calculate the characteristic frequency fe, Ro and Roo. A large increase in fc value was observed regardless of the site of measurement upon initial exposure to hypoxia, followed by a gradual increase, recovering back to the original value upon coming back. In this way we can deduce that the body composition change during acute exposure to hypoxia and heavy exercise during climbing and trekking. The individual analysis of the trunk is compulsory to assess the body fluid composition change. But due to the anthropometric factors, the trunk measurements are not reliable. However a higher percent variation in the resistance of the trunk R compared to the arms at 5kHz measurement is explained by a change in extracellular fluid composition and the trace of the trunk measurement changes which display a decrease followed by a recovery in the acclimatization and returning back suggests a local edema, probably in the lungs which remained subclinical to the subjects.

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