Microbial evolution in the chemostat
Başlık çevirisi mevcut değil.
- Tez No: 401085
- Danışmanlar: DR. ROBERT BEARDMORE, DR. IVANA GUDELJ
- Tez Türü: Doktora
- Konular: Matematik, Mathematics
- Anahtar Kelimeler: Belirtilmemiş.
- Yıl: 2010
- Dil: İngilizce
- Üniversite: University of London
- Enstitü: Yurtdışı Enstitü
- Ana Bilim Dalı: Belirtilmemiş.
- Bilim Dalı: Belirtilmemiş.
- Sayfa Sayısı: 156
Özet
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Özet (Çeviri)
Due to their large populations and short generation times, evolution can be observed within days in microbial populations. They can be easily manipulated and propagated for many generations in the laboratory, enabling a high degree of experimental control over the conditions under which they evolve. As a result, evolutionary experiments with microbes are commonly employed as model systems for testing evolutionary theory in vitro. The chemostat is one experimental setup used for this cause and it allows for sustained communities of microbes in homogenous environments. In this thesis, we develop a mathematical framework for modelling the in-chemostat evolution of microbial communities by incorporating aspects of microbial physiology, density dependent evolution, interactions between di erent species and variation created through mutations into a single dynamical system. We apply our approach to the modelling of three di erent communities within the chemostat in order to pinpoint how evolutionary and ecological processes interact to shape populations, communities and the environments they occupy. Speci cally, we seek answers to the following two questions: (1) What is the minimal environmental structure required to generate and maintain diversity within populations? (2) What are the possible causes of the variation observed in the correlation between the productivity and the diversity of ecological communities?
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