Farklı O2 (Oksijen) konsantrasyonlarının basınç kontrollü ters orantılı ventilasyon modunda (PC-İRV) intrapulmoner şanta etkisi
Başlık çevirisi mevcut değil.
- Tez No: 49621
- Danışmanlar: DOÇ.DR. HASAN AKMAN
- Tez Türü: Tıpta Uzmanlık
- Konular: Anestezi ve Reanimasyon, Göğüs Hastalıkları, Anesthesiology and Reanimation, Chest Diseases
- Anahtar Kelimeler: Belirtilmemiş.
- Yıl: 1996
- Dil: Türkçe
- Üniversite: Çukurova Üniversitesi
- Enstitü: Tıp Fakültesi
- Ana Bilim Dalı: Belirtilmemiş.
- Bilim Dalı: Belirtilmemiş.
- Sayfa Sayısı: 43
Özet
SUMMARY Ten patients were included in this study who did not have any diffuse paranchimal pulmonary pathologies but supported by mechanic ventilation for respiratory insuffiency. Patients were entubated for mechanic ventilation after intravenous administration of penthotal (7 mg/kg) and lysthenon (1-2 mg/kg). Patients were supported by a ventilator in CMV mode. After the insersion of a canule in the radial artery; sistolic, diastolic and mean arterial pressures were obserwed and blood gases were analysed. A Swan-Ganz cathether was introduced via the internal jugular vena. In order to perform a reversed ranged ventilation mode the pressure of the ventilator was adjusted as follows: İ/E as 2/1, TV as 10-12 ml/kg and f as 10 ventilation number/min. Fi02 was raised from 0.2 up to 1.0 by a latency period of 30 minutes ventilation in every Fi02 raise and blood samples were taken from pulmonary and radial arteries. Blood gas values were observed. Arterial 02 pressure (Pa02), arterial 02 saturation (Sa02), pulmonary artery pressure (Pv02), pulmonary artery saturation (Sv02) arterial C02 pressure (PaC02), mean arterial pressure (MAP), central venous pressure (CVP), heart rate (HR), mean pulmonary arterial pressure (MPAP), pulmonary arterial occlussion pressure (PAOP) were all recorded. Cardiac output was measured by termodilution method (Oxymetric 3 Abbott). Cardiac output (CD), Cardiac index (CI), arterial 02 (CaOj), pulmonary arter 02 (Cv02), pulmonary vascular resistance (PVR), systemic vascular resistance(SVR) were automatically recorded. Intrapulmonary shunt calculation was made according to the above values. The intrapulmonary shunt percentage in Fi02 : 0.21 group was accepted as the control group. The difference that was observed between Fi02 increase and the values of MAP, CVP, HR, MPAP, PAOP, CDI, CI, SVR, PVR, PaC02 was not statistically 37significant (p>0.05). Besides Fi02 increase, the values of Pa02, Sa02, Pv02, Sv02, Pa02, Ca02, and Cv02 were also increased (p< 0.001). Percentage of shunt was changed with the increase in Fi02. When Fi02 was increased up to 0.40 the percentage of the shunt decreased and stayed constant when FiOz was equal to 0.50. When Fi02 raised over 0.60 the percentage of shunt was also increased. As a result, it was assessed that Fi02 concentrations were not affecting the cardiovascular parameters. But intrapulmonary shunt values were decreased when Fi02 pressures were up to 0.40 and increased when Fi02 was 0.60. For this reason pulmonary functions should be evaluated when Fi02 was 0.60. Besides, Fi02 should be decreased in order to gain a satisfactory 02 pressure value for the patients. 38
Özet (Çeviri)
SUMMARY Ten patients were included in this study who did not have any diffuse paranchimal pulmonary pathologies but supported by mechanic ventilation for respiratory insuffiency. Patients were entubated for mechanic ventilation after intravenous administration of penthotal (7 mg/kg) and lysthenon (1-2 mg/kg). Patients were supported by a ventilator in CMV mode. After the insersion of a canule in the radial artery; sistolic, diastolic and mean arterial pressures were obserwed and blood gases were analysed. A Swan-Ganz cathether was introduced via the internal jugular vena. In order to perform a reversed ranged ventilation mode the pressure of the ventilator was adjusted as follows: İ/E as 2/1, TV as 10-12 ml/kg and f as 10 ventilation number/min. Fi02 was raised from 0.2 up to 1.0 by a latency period of 30 minutes ventilation in every Fi02 raise and blood samples were taken from pulmonary and radial arteries. Blood gas values were observed. Arterial 02 pressure (Pa02), arterial 02 saturation (Sa02), pulmonary artery pressure (Pv02), pulmonary artery saturation (Sv02) arterial C02 pressure (PaC02), mean arterial pressure (MAP), central venous pressure (CVP), heart rate (HR), mean pulmonary arterial pressure (MPAP), pulmonary arterial occlussion pressure (PAOP) were all recorded. Cardiac output was measured by termodilution method (Oxymetric 3 Abbott). Cardiac output (CD), Cardiac index (CI), arterial 02 (CaOj), pulmonary arter 02 (Cv02), pulmonary vascular resistance (PVR), systemic vascular resistance(SVR) were automatically recorded. Intrapulmonary shunt calculation was made according to the above values. The intrapulmonary shunt percentage in Fi02 : 0.21 group was accepted as the control group. The difference that was observed between Fi02 increase and the values of MAP, CVP, HR, MPAP, PAOP, CDI, CI, SVR, PVR, PaC02 was not statistically 37significant (p>0.05). Besides Fi02 increase, the values of Pa02, Sa02, Pv02, Sv02, Pa02, Ca02, and Cv02 were also increased (p< 0.001). Percentage of shunt was changed with the increase in Fi02. When Fi02 was increased up to 0.40 the percentage of the shunt decreased and stayed constant when FiOz was equal to 0.50. When Fi02 raised over 0.60 the percentage of shunt was also increased. As a result, it was assessed that Fi02 concentrations were not affecting the cardiovascular parameters. But intrapulmonary shunt values were decreased when Fi02 pressures were up to 0.40 and increased when Fi02 was 0.60. For this reason pulmonary functions should be evaluated when Fi02 was 0.60. Besides, Fi02 should be decreased in order to gain a satisfactory 02 pressure value for the patients. 38
Benzer Tezler
- Comparison of some physical and physiological parameters of Ethiopian and Turkish elite distance athletes
Etiyopya ve Türk elit mesafe sporcularinin bazi fiziksel ve fizyolojik parametrelerinin karşilaştirilmasi
GETAYE FISSEHA GELAW
Doktora
İngilizce
2022
SporGazi ÜniversitesiBeden Eğitimi ve Spor Ana Bilim Dalı
PROF. DR. HALİL İBRAHİM CİCİOĞLU
- Oksi yanma şartlarında oluşan karbondioksidin soğutma/sıkıştırma yöntemiyle tutulması üzerine deneysel çalışmalar
Experimental studies on cooling/compressing of carbon dioxide captured from oxy combustion
BERK ÇELİKTAŞ
Yüksek Lisans
Türkçe
2016
Kimya Mühendisliğiİstanbul Teknik ÜniversitesiKimya Mühendisliği Ana Bilim Dalı
PROF. DR. HASAN CAN OKUTAN
- Encapsulation of echium oil and saffron extract in electrospun nanofibers
Echıum yağı ve safran ekstraktının elektroeğrilmiş nanoliflerde enkapsülasyonu
ZAHRA NAJAFI
Doktora
İngilizce
2022
Gıda Mühendisliğiİstanbul Teknik ÜniversitesiGıda Mühendisliği Ana Bilim Dalı
PROF. DR. NEŞE ŞAHİN YEŞİLÇUBUK
PROF. DR. FİLİZ ALTAY
- Kuru incirlerde küf florası ve aflatoksigenik küflerin saptanması
Başlık çevirisi yok
SİBEL BÜYÜKŞİRİN
- Modeling of oxygen–enriched and oxy–combustion of lignite in cfbc and verification with experiments
Linyitin dolaşımlı akışkan yatakta oksijence zenginleştirilmiş ve oksi yanmasının modellenmesi ve modelin deneylerle doğrulanması
DUYGU GÜNDÜZ RAHEEM
Doktora
İngilizce
2020
Makine MühendisliğiMarmara ÜniversitesiMakine Mühendisliği Ana Bilim Dalı
PROF. DR. ZEYNEP SİBEL ÖZDOĞAN
DR. ÖĞR. ÜYESİ BARIŞ YILMAZ