Van bölgesinde özofagus kanserlerinde yaşam süresine bazı prognostik faktörlerin ve tedavi modalitelerinin etkisinin retrospesifik analizi
Retrospective analysis of the effects of same prognostic factors and the therapetic modalities on survival of the esophagus cancer patients in Van region
- Tez No: 224529
- Danışmanlar: DOÇ. DR. MAHMUT İLHAN
- Tez Türü: Tıpta Uzmanlık
- Konular: Onkoloji, Oncology
- Anahtar Kelimeler: Belirtilmemiş.
- Yıl: 2007
- Dil: Türkçe
- Üniversite: Yüzüncü Yıl Üniversitesi
- Enstitü: Tıp Fakültesi
- Ana Bilim Dalı: İç Hastalıkları Ana Bilim Dalı
- Bilim Dalı: Belirtilmemiş.
- Sayfa Sayısı: 76
Özet
Esophageal cancers are more prevalent in some regions of the world which are associated with a high mortality. They are among most common malignancies observed in our region. İn this study, we aimed to describe prognostic factors which may influence the survival of esophageal cancer patients. 356 esophagus cancer patients that recorded in medical oncology policlinic of school of medicine in University hospital of Yuzuncu Yil University were retrospectively evaluated. The data of 292 patients whose survival results could be obtained were evaluated. The effect of different treatment modalities and clinicopathologic parameters on the survival was searched. The median age is 56, 52.8% of patients were women and 47.2% men. The 74.7% of patients were squamous cell carcinoma and the remaining 25.3% adenocarcinoma. 32.5% of patients were localized, 39.7% locally-advanced and 27.3% were found to be metastatic at the time of diagnosis. Of patients, 4.8% proximal, 46.1% middle and 48% distal part of esophagus were involved. The 46 patients were underwent surgery alone, 96 only chemotherapy, 51 primary curative chemoradiotherapy, 35 surgery plus chemotherapy and 20 patients were underwent surgery plus chemoradiotherapy. The median survival was 13 months and 1 and 3 year survival rates were 55% and 9% respectively. When we look at local and locally-advanced stage, median survival was 15 months, 1 and 3 year survival rates were 62% and 12% respectively. On contrary, median survival was 8 months, 1 and 3 year survival rates were 36% and 0% respectively. In univariate analysis, the stage, tumor length, the therapy given, the applied surgery type and the number of chemotherapy cycles were found to be related to survival (p
Özet (Çeviri)
Esophageal cancers are more prevalent in some regions of the world which are associated with a high mortality. They are among most common malignancies observed in our region. İn this study, we aimed to describe prognostic factors which may influence the survival of esophageal cancer patients. 356 esophagus cancer patients that recorded in medical oncology policlinic of school of medicine in University hospital of Yuzuncu Yil University were retrospectively evaluated. The data of 292 patients whose survival results could be obtained were evaluated. The effect of different treatment modalities and clinicopathologic parameters on the survival was searched. The median age is 56, 52.8% of patients were women and 47.2% men. The 74.7% of patients were squamous cell carcinoma and the remaining 25.3% adenocarcinoma. 32.5% of patients were localized, 39.7% locally-advanced and 27.3% were found to be metastatic at the time of diagnosis. Of patients, 4.8% proximal, 46.1% middle and 48% distal part of esophagus were involved. The 46 patients were underwent surgery alone, 96 only chemotherapy, 51 primary curative chemoradiotherapy, 35 surgery plus chemotherapy and 20 patients were underwent surgery plus chemoradiotherapy. The median survival was 13 months and 1 and 3 year survival rates were 55% and 9% respectively. When we look at local and locally-advanced stage, median survival was 15 months, 1 and 3 year survival rates were 62% and 12% respectively. On contrary, median survival was 8 months, 1 and 3 year survival rates were 36% and 0% respectively. In univariate analysis, the stage, tumor length, the therapy given, the applied surgery type and the number of chemotherapy cycles were found to be related to survival (p
Benzer Tezler
- Van ili ve çevresindeki malign tümörlerin demografik özelliklerine göre dağılımının belirlenmesi
Determination of distribution of malignant tumors in van province and its surrounding area according to demographic characteristics
AYVAZ YELER
Tıpta Uzmanlık
Türkçe
2020
İç HastalıklarıVan Yüzüncü Yıl Üniversitesiİç Hastalıkları Ana Bilim Dalı
DR. ÖĞR. ÜYESİ AYDIN AYTEKİN
- Özofagus kanserinde neo-adjuvan kemoradyoterapinin patolojik evre üzerine etkisi
The effect of neo-adjuvan chemoradyotherapy on the pathological stage of esophageal cancer
MAHMUT BARAN YERLİKAYA
Tıpta Uzmanlık
Türkçe
2017
Genel CerrahiYüzüncü Yıl ÜniversitesiGenel Cerrahi Ana Bilim Dalı
YRD. DOÇ. DR. ÖZTEKİN ÇIKMAN
- Van Gölü havzasında gözlenen asbest formlu lifsi minerallerin dağılımları ve insan sağlığı üzerine olası etkileri
The dispersion of asbestos formed fibrous minerals in Van Lake and their possible effects on human health
ÖZLEM TÜRKOĞLU
Yüksek Lisans
Türkçe
2006
Jeoloji MühendisliğiYüzüncü Yıl ÜniversitesiJeoloji Mühendisliği Ana Bilim Dalı
PROF.DR. ARİF ÜMİT TOLLUOĞLU
- Mide veya özofagus kanseri tanısı konulmuş hastaların sosyoekonomik ve eğitim durumlarının tüik verileri ile analizi
Analysis of the socioeconomic and educational status of patients diagnosed with stomach or esophagus cancer with tuik data
ÜMİT ÇİFTÇİ
Tıpta Uzmanlık
Türkçe
2023
GastroenterolojiVan Yüzüncü Yıl Üniversitesiİç Hastalıkları Ana Bilim Dalı
DOÇ. DR. MESUT AYDIN
- Türkiye'nin Doğu Anadolu popülasyonunda özofagus kanseri ve P21 polimorfizmleri arasındaki ilişki
Relationship between esophageal cancer and p21 polymorphisms in Eastern Anatolia population of Turkey
BURAK MUĞDAT KARAN
Yüksek Lisans
Türkçe
2018
Tıbbi BiyolojiVan Yüzüncü Yıl ÜniversitesiTıbbi Biyoloji Ana Bilim Dalı
DR. ÖĞR. ÜYESİ ZEHRA KAYA